Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.54 |
| ▸ | AXL | P30530 | 4/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993662 | 0.94 | MAPK9 (0.48) | BRD4AXLEGFRALK | |
| SCHEMBL24992488 | 0.93 | EGFR (0.53) | BRD4EGFRALK | |
| SCHEMBL24993090 | 0.92 | BRD4 (0.44) | BRD4EGFRALK | |
| SCHEMBL24993046 | 0.91 | FLT3 (0.48) | BRD4EGFRJAK2 | |
| SCHEMBL24993663 | 0.91 | EGFR (0.48) | BRD4EGFRJAK2 | |
| SCHEMBL24992472 | 0.91 | BRD4 (0.55) | BRD4AXLNEK2EGFRALK | |
| SCHEMBL24992324 | 0.91 | BRD4 (0.42) | BRD4EGFRJAK2 | |
| SCHEMBL24992460 | 0.90 | BRD4 (0.41) | BRD4EGFRALKJAK2 | |
| SCHEMBL24992309 | 0.88 | BRD4 (0.65) | BRD4AXLNEK2EGFRALK | |
| SCHEMBL24992306 | 0.88 | EGFR (0.54) | BRD4EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |