Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.52 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | PKD1 | P98161 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993062 | 0.88 | EGFR (0.61) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL24993687 | 0.86 | EGFR (0.56) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL26380188 | 0.85 | EGFR (0.68) | EGFR | |
| SCHEMBL24992455 | 0.83 | EGFR (0.69) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL30014786 | 0.83 | EGFR (0.69) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL24992487 | 0.82 | EGFR (0.62) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL24993179 | 0.82 | EGFR (0.55) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL24993061 | 0.82 | EGFR (0.69) | EGFRCHEK1AURKACCNT1JAK2 | |
| SCHEMBL30015407 | 0.82 | EGFR (0.55) | EGFR | |
| SCHEMBL27076050 | 0.82 | EGFR (0.55) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |