Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993175 | 0.93 | EGFR (0.61) | EGFRMETCHEK1AURKACCNT1 | |
| SCHEMBL24993084 | 0.92 | EGFR (0.53) | EGFRMETINSRIGF1RALK | |
| SCHEMBL25789214 | 0.89 | EGFR (0.57) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24993075 | 0.88 | EGFR (0.53) | EGFRMETCHEK1AURKACCNT1 | |
| SCHEMBL24993057 | 0.87 | EGFR (0.57) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24993058 | 0.87 | EGFR (0.56) | EGFRMETCHEK1AURKACCNT1 | |
| SCHEMBL24992455 | 0.86 | EGFR (0.69) | EGFRMETCHEK1AURKACCNT1 | |
| SCHEMBL24993148 | 0.86 | EGFR (0.61) | EGFRMETINSRIGF1RALK | |
| SCHEMBL30014786 | 0.86 | EGFR (0.69) | EGFRMETCHEK1AURKACCNT1 | |
| SCHEMBL24993076 | 0.85 | EGFR (0.51) | EGFRMETCHEK1AURKACCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |