Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993148 | 0.94 | EGFR (0.61) | EGFRMETALKINSRIGF1R | |
| SCHEMBL24993179 | 0.94 | EGFR (0.55) | EGFRMET | |
| SCHEMBL24993676 | 0.93 | EGFR (0.54) | EGFRMETBRD4 | |
| SCHEMBL24993180 | 0.91 | EGFR (0.53) | EGFRMET | |
| SCHEMBL24993075 | 0.91 | EGFR (0.53) | EGFRMET | |
| SCHEMBL24993675 | 0.90 | EGFR (0.53) | EGFRALK | |
| SCHEMBL27075983 | 0.90 | EGFR (0.58) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30015267 | 0.90 | EGFR (0.58) | EGFRMETALKINSRIGF1R | |
| SCHEMBL24992297 | 0.90 | EGFR (0.57) | EGFRMETALKINSRIGF1R | |
| SCHEMBL24993673 | 0.88 | EGFR (0.48) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |