SCHEMBL24993437

SCHEMBL24993437

c1ccc(-c2nc(-c3ccc(-c4cccc5c4sc4ccccc45)cc3)cc(-c3ccc4c(c3)-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
MAPT P10636 7/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
GLA P06280 1/20 0.39
NTSR1 P30989 1/20 0.34
PRKDC P78527 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
LIMK1 P53667 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
OPRK1 P41145 1/20 0.31
PARP14 Q460N5 1/20 0.31
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
AGTR1 P30556 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23032716 0.93 ALOX5 (0.44) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL23032745 0.92 ALOX5 (0.43) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL23032709 0.90 ALOX5 (0.41) ALOX5MAPTMEN1KMT2AKDM4E
SCHEMBL23032715 0.90 ALOX5 (0.41) ALOX5MAPTMEN1KMT2AKDM4E
SCHEMBL23032804 0.90 ALOX5 (0.41) ALOX5MAPTMEN1KMT2AKDM4E
SCHEMBL25535062 0.89 ALOX5 (0.37) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL23032807 0.89 ALOX5 (0.41) ALOX5MAPTMEN1KMT2AKDM4E
SCHEMBL25534993 0.89 ALOX5 (0.41) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL23032713 0.89 ALOX5 (0.44) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL23032708 0.88 ALOX5 (0.43) ALOX5MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230045583-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC APPARATUS, AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2023-02-09 US disclosed