Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27046397 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL12338498 | 0.98 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL12344338 | 0.98 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL12086377 | 0.98 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL9278052 | 0.87 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL18183280 | 0.83 | TSHR (0.48) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL5090025 | 0.83 | TSHR (0.48) | CHRM2CHRM4CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL2555395 | 0.82 | — | — | |
| SCHEMBL25251769 | 0.82 | SMN1; SMN2 (0.60) | CHRM2CHRM5SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL93509 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |