Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18183280 | 1.00 | TSHR (0.48) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9278052 | 0.95 | CHRM2 (0.48) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| Dioxane SCHEMBL29249400 | 0.91 | TSHR (0.56) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| Oxirane SCHEMBL2819364 | 0.88 | TSHR (0.59) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12344338 | 0.85 | CHRM2 (0.46) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12338498 | 0.85 | CHRM2 (0.46) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12086377 | 0.85 | CHRM2 (0.46) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL24993495 | 0.83 | CHRM2 (0.47) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL27046397 | 0.83 | CHRM2 (0.47) | TSHRCHRM2CHRM4CHRM5CHRM3 | |
| Fluoride SCHEMBL28767217 | 0.83 | TSHR (0.65) | TSHRCHRM2CHRM5ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170015-A1 | EPOXY DERIVATIVES OF ION CHELATING LIGANDS, THEIR POLYMERIC CONJUGATES AND MEDICAL USES THEREOF | KOMPLEXIS S.R.L (IT) | 2016-10-27 | — | — | WO | disclosed |
| US-7390863-B2 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED (US) | 2008-06-24 | — | — | US | disclosed |
| US-7390863-B2 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED (US) | 2008-06-24 | — | — | US | disclosed |
| US-7390863-B2 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED (US) | 2008-06-24 | — | — | US | disclosed |
| US-20070049713-A1 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-03-01 | — | — | US | disclosed |
| US-20070049713-A1 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-03-01 | — | — | US | disclosed |
| US-20070049713-A1 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-03-01 | — | — | US | disclosed |