Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992453 | 0.93 | EGFR (0.54) | EGFRJAK2 | |
| SCHEMBL24993060 | 0.92 | EGFR (0.47) | EGFRBRD4 | |
| SCHEMBL24993046 | 0.91 | FLT3 (0.48) | EGFRBRD4JAK2JAK3 | |
| SCHEMBL24992458 | 0.91 | BRD4 (0.54) | EGFRBRD4JAK2 | |
| SCHEMBL24992460 | 0.91 | BRD4 (0.41) | EGFRBRD4JAK2 | |
| SCHEMBL24992324 | 0.91 | BRD4 (0.42) | EGFRBRD4JAK2 | |
| SCHEMBL24993045 | 0.87 | JAK2 (0.45) | EGFRBRD4JAK2JAK3 | |
| SCHEMBL24992488 | 0.85 | EGFR (0.53) | EGFRBRD4 | |
| SCHEMBL24993662 | 0.85 | MAPK9 (0.48) | EGFRBRD4 | |
| SCHEMBL24993664 | 0.84 | EGFR (0.41) | EGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |