Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.40 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992461 | 0.94 | ALK (0.43) | ALKMETBRD4JAK3STK17B | |
| SCHEMBL24993670 | 0.91 | PTK2 (0.38) | ALKMETJAK3JAK2JAK1 | |
| SCHEMBL24993688 | 0.91 | STK17A (0.44) | ALKMETBRD4STK17BSTK17A | |
| SCHEMBL24993191 | 0.85 | EGFR (0.41) | EGFRPTK2BTK | |
| SCHEMBL24993662 | 0.84 | MAPK9 (0.48) | ALKBRD4EGFRPTK2 | |
| SCHEMBL24992458 | 0.83 | BRD4 (0.54) | ALKBRD4JAK2EGFR | |
| SCHEMBL24993090 | 0.83 | BRD4 (0.44) | ALKMETBRD4EGFR | |
| SCHEMBL24993664 | 0.82 | EGFR (0.41) | METJAK2STK17AEGFRPTK2 | |
| SCHEMBL24992491 | 0.81 | PTK2 (0.40) | ALKMETBRD4FLT3STK17B | |
| SCHEMBL24992309 | 0.78 | BRD4 (0.65) | ALKBRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |