SCHEMBL2499451

SCHEMBL2499451

CCCCOC(=O)C(C=CC#N)=CC=CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.53
ATM Q13315 1/20 0.46
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.37
PTPN1 P18031 2/20 0.37
ALDH1A1 P00352 1/20 0.34
ZDHHC20 Q5W0Z9 2/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
KDM4E B2RXH2 1/20 0.33
APP P05067 1/20 0.33
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL251166 0.87 KDM4E (0.41) HCAR2ATMMAPTTSHRHPGD
SCHEMBL8002027 0.86 HCAR2 (0.47) HCAR2MAPTRAB9ANPSR1TSHR
SCHEMBL11968707 0.84 TSHR (0.45) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7092985 0.83 TSHR (0.47) HCAR2ATMTSHRPTPN1ALDH1A1
SCHEMBL10448731 0.83 ATM (0.45) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL6707462 0.82 TSHR (0.53) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL891995 0.82 KDM4E (0.55) HCAR2ATMMAPTTSHRHPGD
SCHEMBL11309597 0.81 HCAR2 (0.51) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL11314620 0.80 ATM (0.45) HCAR2ATMMAPTRAB9ANPSR1
Acrylic Acid SCHEMBL19409891 0.79 TSHR (0.52) HCAR2ATMTSHRPTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2766438-B1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF INEOS EUROPE AG (CH) 2016-04-20 EP claimed
US-20140275391-A1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF BARCLAYS BANK PLC (GB) 2014-09-18 US claimed
EP-2766438-A1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF Ineos Europe AG (CH) 2014-08-20 EP claimed
WO-2013053895-A1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF INEOS EUROPE AG (CH) 2013-04-18 WO claimed
EP-3916773-A1 COMPOSITION, THERMALLY-CONDUCTIVE SHEET, AND DEVICE EQUIPPED WITH THERMALLY-CONDUCTIVE LAYER FUJIFILM Corporation (JP) 2021-12-01 EP disclosed
US-20210301180-A1 COMPOSITION, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2021-09-30 US disclosed
CN-108795208-A Preparation method of flame-retardant water-based core-shell acrylate resin coating and paint 段宝荣 2018-11-13 CN disclosed
CN-106256838-A Metal ionomer polymer 施乐公司 2016-12-28 CN disclosed
US-9434844-B2 Additive, composition comprising it and use thereof INEOS EUROPE AG (CH) 2016-09-06 US disclosed
EP-2766438-B1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF INEOS EUROPE AG (CH) 2016-04-20 EP disclosed
US-20140272703-A1 TRIBOELECTRIC CHARGE CONTROL OF TONER THROUGH MONOMER RATIO OF SHELL LATEX XEROX CORPORATION (US) 2014-09-18 US disclosed
US-20140275391-A1 ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF BARCLAYS BANK PLC (GB) 2014-09-18 US disclosed
US-20050175833-A1 Pressure-sensitive adhesive sheets for removal of solvent-containing substance NITTO DENKO CORPORATION 2005-08-11 US disclosed
US-5238800-A Curls in direction of back coating side which has specified specific surface resistance KONICA CORPORATION (JP) 1993-08-24 US disclosed
EP-0491176-A1 Silver halide photographic light-sensitive material improved in anti-jamming property KONICA CORPORATION (JP) 1992-06-24 EP disclosed
US-5084339-A Electroconductive polymer, hydrophobic polymer with polyoxyalk ylene oxide side chain, photographic film KONICA CORPORATION (JP) 1992-01-28 US disclosed
US-5066708-A Emulsionpolymerization of thermoplastic resin ROHM AND HAAS COMPANY (US) 1991-11-19 US disclosed
US-5008324-A Novel damping compositions ROHM AND HAAS COMPANY (US) 1991-04-16 US disclosed
EP-0398223-A2 Antistatic layer KONICA CORPORATION (JP) 1990-11-22 EP disclosed
US-4273552-A Process for the pretreatment of cellulose fibers to be printed according to the thermotransfer printing method HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-16 US disclosed