Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30314030 | 1.00 | BCL2 (0.62) | BCL2BCL2L1 | |
| SCHEMBL3395330 | 0.95 | BCL2 (0.63) | BCL2 | |
| SCHEMBL30314016 | 0.90 | BCL2 (0.66) | BCL2BCL2L1 | |
| SCHEMBL1957515 | 0.90 | BCL2 (0.61) | BCL2 | |
| SCHEMBL30314083 | 0.90 | BCL2 (0.61) | BCL2 | |
| SCHEMBL2484548 | 0.89 | BCL2 (0.54) | BCL2 | |
| SCHEMBL2725665 | 0.86 | BCL2 (0.67) | BCL2BCL2L1 | |
| SCHEMBL30314074 | 0.86 | BCL2 (0.68) | BCL2BCL2L1 | |
| SCHEMBL30313826 | 0.86 | BCL2 (0.68) | BCL2BCL2L1 | |
| SCHEMBL30313869 | 0.86 | BCL2 (0.64) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507229-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-2376480-A2 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |