Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25010693 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSCDK1CDK2 | |
| SCHEMBL25001112 | 0.83 | CYP1A2 (0.38) | MCHR1DHFRDCPSPOLBTDP1 | |
| SCHEMBL30271340 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSCDK1CDK2 | |
| SCHEMBL25010689 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSCDK1CDK2 | |
| SCHEMBL25000973 | 0.82 | PDE10A (0.40) | MCHR1POLBTDP1CDK1CDK2 | |
| SCHEMBL25001416 | 0.81 | MCHR1 (0.37) | MCHR1DHFRDCPSPOLBTDP1 | |
| SCHEMBL25001074 | 0.77 | POLB (0.39) | POLBTDP1HDAC3HDAC1SIRT2 | |
| SCHEMBL30168387 | 0.77 | POLB (0.39) | POLBTDP1HDAC3HDAC1SIRT2 | |
| SCHEMBL656848 | 0.75 | POLB (0.50) | POLBTDP1HDAC3HDAC1PDE10A | |
| SCHEMBL30054640 | 0.75 | POLB (0.50) | POLBTDP1HDAC3HDAC1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023014907-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |