Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25010689 | 1.00 | MCHR1 (0.43) | MCHR1DHFRDCPSKDM4EUSP2 | |
| SCHEMBL30271340 | 1.00 | MCHR1 (0.43) | MCHR1DHFRDCPSKDM4EUSP2 | |
| SCHEMBL25009544 | 0.83 | MCHR1 (0.39) | MCHR1DHFRDCPSKDM4EUSP2 | |
| SCHEMBL25001065 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSCDK1CDK2 | |
| SCHEMBL29983687 | 0.79 | CCNA2 (0.37) | MCHR1KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL23458439 | 0.79 | CCNA2 (0.37) | MCHR1KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL29210854 | 0.75 | CTSB (0.43) | MCHR1HPGDCDK1CDK2KDR | |
| SCHEMBL29210853 | 0.75 | CTSB (0.43) | MCHR1HPGDCDK1CDK2KDR | |
| SCHEMBL15716080 | 0.75 | TSHR (0.47) | HSD17B10TLR7ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL2368572 | 0.74 | MCHR1 (0.43) | MCHR1DHFRDCPSCDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043041-A | LPAR1 antagonists and uses thereof | 康蒂内乌姆医疗公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |