Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 20/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001526 | 0.91 | LPAR1 (0.32) | LPAR1CYP3A4 | |
| SCHEMBL25001069 | 0.85 | LPAR1 (0.35) | LPAR1CYP3A4 | |
| SCHEMBL25001522 | 0.77 | NPC1 (0.37) | LPAR1CYP3A4 | |
| SCHEMBL30168357 | 0.74 | LPAR1 (0.34) | LPAR1CYP3A4 | |
| SCHEMBL25001066 | 0.74 | LPAR1 (0.39) | LPAR1CYP3A4 | |
| SCHEMBL30168354 | 0.69 | LPAR1 (0.41) | LPAR1CYP3A4 | |
| SCHEMBL25001523 | 0.69 | LPAR1 (0.41) | LPAR1CYP3A4 | |
| SCHEMBL25001486 | 0.64 | LPAR1 (0.38) | LPAR1CYP3A4 | |
| SCHEMBL30168397 | 0.63 | KDM1A (0.44) | LPAR1CYP3A4LPAR2LPAR3 | |
| SCHEMBL25001440 | 0.63 | LPAR1 (0.40) | LPAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014907-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |