Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | USP1 | O94782 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001079 | 1.00 | KDM1A (0.44) | KDM1ATSHRALOX15ATMLPAR1 | |
| SCHEMBL29573207 | 0.83 | TSHR (0.54) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL21582517 | 0.83 | TSHR (0.54) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL29573084 | 0.78 | TSHR (0.43) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL22805785 | 0.78 | TSHR (0.43) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL11914841 | 0.76 | TSHR (0.48) | KDM1ATSHRALOX15ATMHSD17B10 | |
| SCHEMBL30168356 | 0.76 | LPAR1 (0.53) | LPAR1CYP3A4 | |
| SCHEMBL30168425 | 0.75 | SCD5 (0.41) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL25001165 | 0.75 | SCD5 (0.41) | TSHRALOX15ATMLPAR1CYP3A4 | |
| SCHEMBL25001066 | 0.72 | LPAR1 (0.39) | ALOX15LPAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014907-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |