Rhodanine-3-Acetic Acid

Rhodanine-3-Acetic Acid

SCHEMBL250012

O=C(O)CN1C(=O)CSC1=S

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 8/20 1.00
GSK3B P49841 8/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
GAA P10253 6/20 0.61
ALDH1A1 P00352 5/20 0.54
RECQL P46063 4/20 0.54
MAPT P10636 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
THRB P10828 2/20 0.54
HTT P42858 2/20 0.54
HSD17B10 Q99714 2/20 0.51
CYP1A2 P05177 1/20 0.51
KDM4E B2RXH2 1/20 0.46
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
PLCG1 P19174 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rhodanine-3-Acetic Acid SCHEMBL2121316 1.00 GSK3A (1.00) GSK3AGSK3BMEN1KMT2AGAA
Rhodanine-3-Acetic Acid SCHEMBL1372027 0.98 GSK3A (0.96) GSK3AGSK3BMEN1KMT2AGAA
Rhodanine-3-Acetic Acid SCHEMBL6011090 0.86 GSK3A (0.74) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL3083931 0.83 GSK3A (0.71) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL3843056 0.83 GSK3A (0.71) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL1279204 0.81 MEN1 (0.77) GSK3AGSK3BMEN1KMT2AGAA
Hydrochloric Acid SCHEMBL28286249 0.80 MEN1 (0.74) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL1421312 0.80 GSK3A (0.67) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL2342390 0.79 GSK3A (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL22532392 0.79 GSK3A (0.65) GSK3AGSK3BMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574285-A Alcohol-soluble bio-based citronella polymer and preparation method and application thereof 武汉纺织大学 2026-02-27 CN claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-117815389-A Photo-thermal response hydrogel and preparation method thereof 天津理工大学 2024-04-05 CN claimed
CN-117624074-A Preparation method of high-purity epalrestat A crystal form 哈药集团技术中心 2024-03-01 CN claimed
CN-117065724-A High-efficient absorption heavy metal ion Pb 2+ Composite material of (2), preparation method and application thereof 乐山师范学院 2023-11-17 CN claimed
CN-116239633-A Carbazole compound containing metal platinum, preparation method and co-sensitization application thereof 浙江工业大学 2023-06-09 CN claimed
CN-110813259-B Antibacterial multifunctional heavy metal ion adsorption membrane and preparation method of heavy metal ion imprinting composite membrane 中冶华天工程技术有限公司 2022-08-30 CN claimed
CN-108191788-B Crystal form B epalrestat and preparation method thereof 石家庄四药有限公司 2022-05-06 CN claimed
CN-113651770-B Epalrestat crystal form, and preparation method and application thereof 山东达因海洋生物制药股份有限公司 2022-04-29 CN claimed
WO-2002022612-A1 THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT OXFORD GLYCOSCIENCES (UK) LIMITED (GB) 2002-03-21 WO claimed
WO-2002017915-A1 BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS OXFORD GLYCOSCIENCES (UK) LIMITED (GB) 2002-03-07 WO claimed
EP-0835233-B1 COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS NEN LIFE SCIENCE PROD INC (US) 2001-12-05 EP claimed
CN-1252707-A Use of unsaturated aldehydes in dying fibers containing keratin HENKEL KGAA (DE) 2000-05-10 CN claimed
US-5843396-A Method for stabilizing radiolabeled organic compounds by adding a separate stabilizing compound NEN LIFE SCIENCE PRODUCTS, INC. (US) 1998-12-01 US claimed
EP-0835233-A1 COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-15 EP claimed
WO-1997001520-A1 COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO claimed
EP-0143461-B1 RHODANINE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Kaken Pharmaceutical Co., Ltd. (JP) 1989-09-06 EP claimed
EP-0258914-A2 Rhodanine derivatives and a process for preparing same TAIHO PHARMACEUTICAL CO., LTD. (JP) 1988-03-09 EP claimed
EP-0143461-A2 Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same Kaken Pharmaceutical Co., Ltd. (JP) 1985-06-05 EP claimed