SCHEMBL25001373

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25044369	0.86	HSD17B10 (0.39)	CYP2D6MAPK1ALDH1A1CYP3A4TSHR
	SCHEMBL24940878	0.86	CYP2D6 (0.37)	CYP2D6SMN1; SMN2ALDH1A1CYP3A4TSHR
	SCHEMBL25820353	0.86	CYP2D6 (0.43)	CYP2D6SMN1; SMN2MAPK1ALDH1A1CYP3A4
	SCHEMBL22477427	0.81	CYP2D6 (0.59)	CYP2D6SMN1; SMN2MAPK1ALDH1A1CYP3A4
	SCHEMBL25044367	0.80	HSD17B10 (0.35)	CYP2D6ALDH1A1CYP3A4TSHRCYP2C9
	SCHEMBL17624329	0.80	CYP2D6 (0.34)	CYP2D6SMN1; SMN2ALDH1A1CYP3A4TSHR
	SCHEMBL10273152	0.80	GAA (0.42)	ALDH1A1SLC6A2
	SCHEMBL20051946	0.79	CYP2D6 (0.38)	CYP2D6SMN1; SMN2MAPK1ALDH1A1CYP3A4
	SCHEMBL18497937	0.78	TSHR (0.46)	CYP2D6SMN1; SMN2ALDH1A1CYP3A4TSHR
	SCHEMBL18517451	0.75	TSHR (0.38)	CYP2D6SMN1; SMN2CYP3A4TSHROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.