Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23441943 | 0.95 | EGFR (0.67) | EGFRALK | |
| SCHEMBL25001552 | 0.94 | EGFR (0.51) | EGFRALKBTK | |
| SCHEMBL25002036 | 0.94 | EGFR (0.52) | EGFRALK | |
| SCHEMBL25001837 | 0.90 | EGFR (0.53) | EGFR | |
| SCHEMBL25001947 | 0.90 | EGFR (0.54) | EGFR | |
| SCHEMBL25001609 | 0.90 | EGFR (0.72) | EGFR | |
| SCHEMBL25002414 | 0.90 | EGFR (0.49) | EGFRBTK | |
| SCHEMBL25001890 | 0.90 | EGFR (0.55) | EGFRBTK | |
| SCHEMBL25002403 | 0.90 | EGFR (0.50) | EGFRBTK | |
| SCHEMBL25002508 | 0.90 | EGFR (0.52) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |