Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001697 | 0.91 | EGFR (0.52) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL25002442 | 0.83 | EGFR (0.54) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL25001385 | 0.82 | EGFR (0.60) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL25002853 | 0.81 | EGFR (0.47) | EGFRBTKMAP4K1CDK19ALK | |
| SCHEMBL25001806 | 0.80 | EGFR (0.49) | EGFRBTKMAP4K1ALK | |
| SCHEMBL25001983 | 0.79 | EGFR (0.57) | EGFRBTKMAP4K1CDK19ALK | |
| SCHEMBL25001789 | 0.79 | EGFR (0.69) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL25001934 | 0.79 | EGFR (0.48) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL25001656 | 0.77 | EGFR (0.48) | EGFRBTKMAP4K1ALKULK1 | |
| SCHEMBL30176224 | 0.76 | EGFR (0.57) | EGFRBTKMAP4K1ALKULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |