Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001403 | 0.89 | EGFR (0.59) | EGFRBTKTTK | |
| SCHEMBL25001890 | 0.86 | EGFR (0.55) | EGFRBTKTTK | |
| SCHEMBL22950947 | 0.86 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL25002442 | 0.85 | EGFR (0.54) | EGFRBTKTTK | |
| SCHEMBL30741317 | 0.84 | EGFR (0.65) | EGFRBTKTTK | |
| SCHEMBL25001544 | 0.84 | EGFR (0.65) | EGFRBTKTTK | |
| SCHEMBL25002757 | 0.84 | EGFR (0.48) | EGFRBTKTTK | |
| SCHEMBL25820802 | 0.83 | EGFR (0.58) | EGFRBTKTTK | |
| SCHEMBL25001345 | 0.82 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL25002032 | 0.82 | EGFR (0.48) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |