Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001804 | 0.90 | EGFR (0.41) | ULK1EGFRBTKJAK2MAP4K1 | |
| SCHEMBL25002848 | 0.85 | EGFR (0.54) | ULK1EGFR | |
| SCHEMBL25001809 | 0.84 | EGFR (0.52) | ULK1EGFR | |
| SCHEMBL25002048 | 0.80 | EGFR (0.67) | EGFR | |
| SCHEMBL25001789 | 0.80 | EGFR (0.69) | ULK1EGFRBTKALKINSR | |
| SCHEMBL25001851 | 0.79 | EGFR (0.40) | ULK1EGFRLRRK2JAK2ALK | |
| SCHEMBL25002992 | 0.78 | EGFR (0.44) | ULK1EGFRLRRK2ALKMAP4K1 | |
| SCHEMBL25002500 | 0.78 | EGFR (0.46) | ULK1EGFRLRRK2JAK2 | |
| SCHEMBL25001861 | 0.78 | ALK (0.55) | EGFRBTKALKINSRIGF1R | |
| SCHEMBL24179098 | 0.75 | EGFR (0.62) | EGFRBTKJAK2ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |