Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.55 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001811 | 0.89 | EGFR (0.54) | EGFR | |
| SCHEMBL25002091 | 0.88 | EGFR (0.56) | EGFR | |
| SCHEMBL25001703 | 0.82 | EGFR (0.66) | ALKEGFRINSRIGF1RMAP4K1 | |
| SCHEMBL25002938 | 0.82 | EGFR (0.59) | EGFR | |
| SCHEMBL25002710 | 0.81 | EGFR (0.56) | EGFR | |
| SCHEMBL25002718 | 0.79 | EGFR (0.57) | EGFR | |
| SCHEMBL25001839 | 0.78 | EGFR (0.45) | EGFR | |
| SCHEMBL25002992 | 0.78 | EGFR (0.44) | ALKEGFRMAP4K1 | |
| SCHEMBL25002391 | 0.78 | ULK1 (0.48) | ALKEGFRINSRIGF1RMAP4K1 | |
| SCHEMBL25001809 | 0.77 | EGFR (0.52) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |