Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314967 | 0.78 | PKM (0.31) | PKM | |
| SCHEMBL25001801 | 0.78 | PKM (0.31) | PKM | |
| SCHEMBL24449009 | 0.76 | PKM (0.38) | PKM | |
| SCHEMBL25002752 | 0.74 | — | — | |
| SCHEMBL18269013 | 0.73 | — | — | |
| SCHEMBL25773782 | 0.73 | — | — | |
| SCHEMBL18269014 | 0.73 | — | — | |
| SCHEMBL16285867 | 0.69 | CHRM3 (0.35) | — | |
| SCHEMBL21567149 | 0.69 | CHRM3 (0.35) | — | |
| SCHEMBL14626849 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |