Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.68 |
| ▸ | NPC1 | O15118 | 11/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428993 | 0.83 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5708525 | 0.80 | KMT2A (1.00) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6340566 | 0.80 | KMT2A (1.00) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8635367 | 0.79 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1262943 | 0.78 | MAPT (0.68) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14607771 | 0.78 | MAPT (0.68) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1262942 | 0.78 | MAPT (0.68) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL964561 | 0.78 | KCNQ3 (0.69) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL964563 | 0.78 | KCNQ3 (0.69) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13790858 | 0.77 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |