Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 10/20 | 0.41 |
| ▸ | CDK2 | P24941 | 10/20 | 0.41 |
| ▸ | CCNK | O75909 | 9/20 | 0.41 |
| ▸ | CDK9 | P50750 | 9/20 | 0.41 |
| ▸ | CCND3 | P30281 | 8/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 8/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147670 | 1.00 | CCNA2 (0.41) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL25005171 | 0.86 | ALK (0.39) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL25004484 | 0.82 | MAPK3 (0.51) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL31147650 | 0.82 | MAPK3 (0.51) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL27237977 | 0.81 | ALK (0.44) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL31147618 | 0.81 | ALK (0.44) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL25005393 | 0.79 | LCK (0.46) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL31147673 | 0.79 | LCK (0.46) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL28658752 | 0.77 | CCNA2 (0.50) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL31147662 | 0.77 | MAPK3 (0.42) | LRRK2MAPK3ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4382514-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023014022-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-02-09 | — | — | WO | disclosed |