Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 8/20 | 0.50 |
| ▸ | CDK2 | P24941 | 8/20 | 0.50 |
| ▸ | CCNK | O75909 | 6/20 | 0.50 |
| ▸ | CDK9 | P50750 | 6/20 | 0.50 |
| ▸ | CCND3 | P30281 | 5/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264974 | 0.89 | TP53 (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL26161918 | 0.88 | CCNA2 (0.63) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL30394901 | 0.88 | CCNA2 (0.63) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL25450128 | 0.83 | CCNA2 (0.46) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL13832188 | 0.81 | CCNA2 (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL21234974 | 0.80 | CCNA2 (0.44) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL2062564 | 0.79 | IGF1R (0.54) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL31147617 | 0.79 | ALK (0.44) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL21235177 | 0.79 | CCNA2 (0.43) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL375419 | 0.79 | ULK1 (0.51) | CCNA2CDK2CCNKCDK9CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-113677680-A | EGFR inhibitor and composition and application thereof | 贝达药业股份有限公司 | 2021-11-19 | — | — | CN | disclosed |