Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308851 | 0.82 | HTT (0.59) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25004783 | 0.80 | HTT (0.41) | HTTALDH1A1TSHR | |
| SCHEMBL23994596 | 0.80 | HTT (0.41) | HTTALDH1A1 | |
| SCHEMBL23995343 | 0.79 | HTT (0.39) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25005722 | 0.79 | HTT (0.44) | HTT | |
| SCHEMBL308513 | 0.78 | HTT (0.56) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL10262809 | 0.76 | HTT (0.48) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL575206 | 0.76 | ALDH1A1 (0.62) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL30181660 | 0.76 | HTT (0.48) | HTTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL26960832 | 0.75 | HTT (0.48) | HTTALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | HTT 4420/4885ALDH1A1 347/4885MEN1 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.