SCHEMBL25005683

SCHEMBL25005683

N#Cc1ccc(-c2cc3c4cc5ccccc5cc4n4c5cc6ccc(-c7ccc8cc9c(cc8c7)c7cc(-c8cc(-c%10ccccc%10)cc(-c%10ccccc%10)c8)cc8c%10cc%11ccccc%11cc%10n9c87)cc6cc5c(c2)c34)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
HRH3 Q9Y5N1 8/20 0.37
MYC P01106 1/20 0.37
PDPK1 O15530 1/20 0.36
ALDH1A3 P47895 1/20 0.36
PGR P06401 2/20 0.36
CHEK1 O14757 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
ENPP3 O14638 1/20 0.35
KAT6A Q92794 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19564965 0.97 CYP17A1 (0.40) CYP17A1CYP11B1CYP11B2HRH3MYC
SCHEMBL21718123 0.97 CYP17A1 (0.40) CYP17A1CYP11B1CYP11B2HRH3MYC
SCHEMBL19564966 0.97 CYP17A1 (0.40) CYP17A1CYP11B1CYP11B2HRH3MYC
SCHEMBL21718126 0.97 CYP17A1 (0.40) CYP17A1CYP11B1CYP11B2HRH3MYC
SCHEMBL21717476 0.92 HRH3 (0.41) CYP17A1CYP11B1CYP11B2HRH3PGR
SCHEMBL19563850 0.91 ENPP3 (0.40) CYP11B2MYCPDPK1ALDH1A3PGR
SCHEMBL19564916 0.90 CYP17A1 (0.39) CYP17A1CYP11B1CYP11B2HRH3ALDH1A3
SCHEMBL19564917 0.90 CYP17A1 (0.39) CYP17A1CYP11B1CYP11B2HRH3ALDH1A3
SCHEMBL19563819 0.90 CYP11B1 (0.45) CYP17A1CYP11B1CYP11B2HRH3PDPK1
SCHEMBL21718124 0.87 HRH3 (0.41) CYP17A1CYP11B1CYP11B2HRH3PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230042023-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 US disclosed