Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.33 |
| ▸ | TP53 | P04637 | 7/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224254 | 1.00 | CSF1R (0.34) | CSF1RMDM2TP53CHRNA7MTOR | |
| SCHEMBL23993442 | 0.90 | MDM2 (0.33) | CSF1RMDM2TP53MTORSYK | |
| SCHEMBL23993440 | 0.90 | MDM2 (0.33) | CSF1RMDM2TP53MTORSYK | |
| SCHEMBL23993857 | 0.89 | MDM2 (0.31) | MDM2MTORSYK | |
| SCHEMBL30224203 | 0.89 | MDM2 (0.31) | MDM2MTORSYK | |
| SCHEMBL30182093 | 0.86 | MDM2 (0.34) | MDM2TP53MTORSYK | |
| SCHEMBL23994491 | 0.86 | MDM2 (0.34) | MDM2TP53MTORSYK | |
| SCHEMBL23994733 | 0.86 | MDM2 (0.36) | MDM2TP53MTORSYK | |
| SCHEMBL23994740 | 0.86 | MDM2 (0.36) | MDM2TP53MTORSYK | |
| SCHEMBL30224472 | 0.86 | MDM2 (0.36) | MDM2TP53MTORSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | CSF1R 2149/4885MDM2 2083/4885TP53 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.