SCHEMBL2500588

SCHEMBL2500588

O=C1Oc2ccccc2OC(=O)c2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.72
ALOX15 P16050 1/20 0.72
TYMS P04818 2/20 0.56
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TSHR P16473 2/20 0.46
PKM P14618 1/20 0.46
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
CDC25B P30305 2/20 0.45
MAPK1 P28482 2/20 0.45
POLB P06746 3/20 0.43
MAOA P21397 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CES2 O00748 1/20 0.43
APAF1 O14727 1/20 0.43
TERT O14746 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2113335 0.89 ALOX15 (0.57) TDP1ALOX15TYMSKDM4EALDH1A1
SCHEMBL30055520 0.89 ALOX15 (0.57) TDP1ALOX15TYMSKDM4EALDH1A1
SCHEMBL167093 0.88
SCHEMBL30320031 0.88 TDP1 (0.63) TDP1ALOX15TYMSKDM4EALDH1A1
SCHEMBL12691224 0.88 TDP1 (0.63) TDP1ALOX15TYMSKDM4EALDH1A1
SCHEMBL19754922 0.88 TDP1 (0.63) TDP1ALOX15TYMSKDM4EALDH1A1
Phthalic Anhydride SCHEMBL29356227 0.84 TDP1 (1.00) TDP1ALOX15TYMSKDM4EALDH1A1
Phthalic Anhydride SCHEMBL220 0.84 TDP1 (1.00) TDP1ALOX15TYMSKDM4EALDH1A1
Phthalic Anhydride SCHEMBL380499 0.84 TDP1 (1.00) TDP1ALOX15TYMSKDM4EALDH1A1
Phthalic Anhydride SCHEMBL1871448 0.81 TDP1 (0.93) TDP1ALOX15TYMSKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153881-B Molded structure of polycarbonate-based substrate overmolded with silicone rubber 盛禧奥欧洲有限责任公司 2020-11-17 CN disclosed
US-9120925-B2 Carbonate blend composition having improved resistance to environmental stress cracking TRINSEO EUROPE GMBH (CH) 2015-09-01 US disclosed
EP-2558536-B1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON EUROPE GMBH (CH) 2014-07-30 EP disclosed
US-20130131257-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON LLC (US) 2013-05-23 US disclosed
EP-2558536-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING Styron Europe GmbH (CH) 2013-02-20 EP disclosed
WO-2011128119-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON EUROPE GMBH (CH) 2011-10-20 WO disclosed
WO-2011130754-A1 CARBONATE BLEND COMPOSITION HAVING IMPROVED RESISTANCE TO ENVIRONMENTAL STRESS CRACKING STYRON EUROPE GMBH (CH) 2011-10-20 WO disclosed
EP-2377899-A1 Carbonate blend compostion having improved resistance to environmental stress cracking Styron Europe GmbH (CH) 2011-10-19 EP disclosed
EP-1165685-A1 POLYPROPYLENE AND POLYESTER BLENDS CONTAINING A GRAFT-MODIFIED POLYOLEFIN ELASTOMER THE DOW CHEMICAL COMPANY (US) 2002-01-02 EP disclosed
WO-2000052094-A1 POLYPROPYLENE AND POLYESTER BLENDS CONTAINING A GRAFT-MODIFIED POLYOLEFIN ELASTOMER THE DOW CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
EP-0450055-A4 IMPROVING THE TOUGHNESS AND PROCESSIBILITY OF HIGH HEAT POLYCARBONATE COMPOSITIONS 1992-09-09 EP disclosed
WO-1992014787-A1 BLENDS OF THERMOPLASTIC MOLDING COMPOSITIONS CONTAINING EPOXY RESINS THE DOW CHEMICAL COMPANY (US) 1992-09-03 WO disclosed
EP-0496876-A1 FILLED THERMOPLASTIC MOLDING COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1992-08-05 EP disclosed
US-5124402-A Polycarbonate, polyester, olefin/carbon monoxide copolymer, mono-alkenyl aromatic/diene block copolymer and grafted core-shell elastomer THE DOW CHEMICAL COMPANY (US) 1992-06-23 US disclosed
WO-1992003507-A1 FILLED THERMOPLASTIC MOLDING COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1992-03-05 WO disclosed
WO-1992003504-A1 THERMOPLASTIC MOLDING COMPOSITIONS WITH IMPROVED SOLVENT RESISTANCE AND IMPACT STRENGTH AND USE THEREOF THE DOW CHEMICAL COMPANY (US) 1992-03-05 WO disclosed
US-5082890-A Polycarbonate, polyester, olefin-carbon monoxide, grafted shell-core and talc THE DOW CHEMICAL COMPANY (US) 1992-01-21 US disclosed
WO-1991018052-A1 POLYCARBONATE/POLYESTER BLENDS WITH IMPROVED THERMAL MELT STABILITY THE DOW CHEMICAL COMPANY (US) 1991-11-28 WO disclosed
WO-1991016379-A1 POLYCARBONATE/AROMATIC POLYESTER BLENDS CONTAINING AN OLEFINIC MODIFIER THE DOW CHEMICAL COMPANY (US) 1991-10-31 WO disclosed
EP-0450055-A1 IMPROVING THE TOUGHNESS AND PROCESSIBILITY OF HIGH HEAT POLYCARBONATE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1991-10-09 EP disclosed