Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 14/20 | 0.66 |
| ▸ | CDK2 | P24941 | 14/20 | 0.66 |
| ▸ | CCNA1 | P78396 | 14/20 | 0.66 |
| ▸ | PAK4 | O96013 | 2/20 | 0.66 |
| ▸ | CDK1 | P06493 | 2/20 | 0.66 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.66 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.66 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.66 |
| ▸ | ULK1 | O75385 | 1/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.66 |
| ▸ | ERCC2 | P18074 | 1/20 | 0.66 |
| ▸ | CCND1 | P24385 | 1/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.66 |
| ▸ | CLK1 | P49759 | 1/20 | 0.66 |
| ▸ | CLK2 | P49760 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095340 | 0.76 | CDK2 (0.56) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL24669470 | 0.75 | CCNA2 (0.82) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL24513389 | 0.72 | CCNA2 (0.66) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL23837261 | 0.67 | CCNA2 (0.54) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL2917754 | 0.65 | CDK2 (0.62) | CCNA2CDK2CCNA1PAK4GSK3B | |
| SCHEMBL23185890 | 0.65 | CCNA2 (0.52) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL23837259 | 0.64 | CDK2 (0.46) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL19312125 | 0.59 | CDK2 (0.46) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL23837264 | 0.59 | CCNA2 (0.48) | CCNA2CDK2CCNA1PAK4CDK1 | |
| SCHEMBL19116481 | 0.59 | MAPK8 (0.39) | CCNA2CDK2CCNA1PAK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129293-A1 | NERVE CELL DEGENERATION INHIBITOR | Kyoto University (JP) | 2023-02-08 | — | — | EP | disclosed |