SCHEMBL25008907

SCHEMBL25008907

c1ccc(-c2ccc3ccc(-c4nc(-c5cccc6ccccc56)nc(-c5cccc6oc7ccccc7c56)n4)cc3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 5/20 0.40
HSD17B10 Q99714 5/20 0.40
MAPT P10636 4/20 0.40
HPGD P15428 3/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 2/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ESR1 P03372 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24887934 0.96 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL24890266 0.95 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL26231355 0.95 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL23821072 0.95 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL23821641 0.94 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL25008989 0.94 ALDH1A1 (0.38) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL26260292 0.94 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL26260289 0.94 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL27368654 0.94 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10MAPTHPGD
SCHEMBL26260396 0.94 PIM1 (0.39) ALDH1A1KDM4EHSD17B10MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289836-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-12-13 EP disclosed
WO-2023014004-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-02-09 WO disclosed