Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13313072 | 1.00 | OPRM1 (0.34) | OPRM1APLNREPHX2 | |
| SCHEMBL12418401 | 1.00 | OPRM1 (0.34) | OPRM1APLNREPHX2 | |
| SCHEMBL12418400 | 1.00 | OPRM1 (0.34) | OPRM1APLNREPHX2 | |
| SCHEMBL12418402 | 1.00 | OPRM1 (0.34) | OPRM1APLNREPHX2 | |
| SCHEMBL10094034 | 1.00 | OPRM1 (0.34) | OPRM1APLNREPHX2 | |
| SCHEMBL13293170 | 0.86 | ESR1 (0.31) | OPRM1APLNR | |
| SCHEMBL13295357 | 0.86 | ESR1 (0.31) | OPRM1APLNR | |
| SCHEMBL13295359 | 0.86 | ESR1 (0.31) | OPRM1APLNR | |
| SCHEMBL19604527 | 0.86 | ESR1 (0.31) | OPRM1APLNR | |
| SCHEMBL13295360 | 0.86 | ESR1 (0.31) | OPRM1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230040182-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230040182-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNB1, KCNJ2, KCNB2 | OPRM1 2165/4885APLNR 4021/4885EPHX2 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.