Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25000973 | 0.89 | PDE10A (0.40) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30271399 | 0.80 | PIK3CD (0.33) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL17372584 | 0.80 | ALDH1A1 (0.37) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL20223512 | 0.80 | ALDH1A1 (0.37) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL29983687 | 0.80 | CCNA2 (0.37) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL23458439 | 0.80 | CCNA2 (0.37) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL16931085 | 0.78 | MCHR1 (0.38) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL29990367 | 0.78 | CCNA2 (0.36) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL25009828 | 0.76 | ALDH1A1 (0.37) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL7823093 | 0.76 | ALDH1A1 (0.34) | ALDH1A1PIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043041-A | LPAR1 antagonists and uses thereof | 康蒂内乌姆医疗公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |