Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125451 | 0.85 | HPGD (0.47) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL17173129 | 0.83 | NR1H2 (0.45) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL17173130 | 0.83 | NR1H2 (0.45) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL12035619 | 0.83 | NR1H2 (0.58) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL15764146 | 0.83 | NR1H2 (0.58) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL15764147 | 0.83 | NR1H2 (0.58) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL13801217 | 0.83 | NR1H2 (0.58) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL16472256 | 0.82 | CHRNB2 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16587760 | 0.82 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL442977 | 0.82 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |