Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868278 | 0.90 | BRD4 (0.40) | BRD4EPHX2TSHRLMNAKDM4E | |
| SCHEMBL6874283 | 0.83 | LMNA (0.47) | BRD4EPHX2TSHRLMNAKDM4E | |
| SCHEMBL20855750 | 0.83 | LMNA (0.47) | BRD4EPHX2TSHRLMNAKDM4E | |
| SCHEMBL16977581 | 0.83 | LMNA (0.47) | BRD4EPHX2TSHRLMNAKDM4E | |
| SCHEMBL337633 | 0.81 | BRD4 (0.44) | BRD4EPHX2TSHRNR1H2GAA | |
| SCHEMBL22483469 | 0.81 | BRD4 (0.44) | BRD4TSHRLMNAKDM4ENR1H2 | |
| SCHEMBL22526606 | 0.81 | BRD4 (0.44) | BRD4EPHX2TSHRNR1H2GAA | |
| SCHEMBL1966116 | 0.81 | BRD4 (0.44) | BRD4EPHX2TSHRNR1H2GAA | |
| SCHEMBL1969174 | 0.81 | BRD4 (0.44) | BRD4EPHX2TSHRNR1H2GAA | |
| SCHEMBL10248813 | 0.81 | BRD4 (0.44) | BRD4TSHRNR1H2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |