Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 15/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139064 | 0.89 | MAPKAPK5 (0.46) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL30171903 | 0.88 | MAPKAPK5 (0.43) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22139098 | 0.88 | MAPKAPK5 (0.43) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22123361 | 0.86 | MAPKAPK5 (0.44) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22142784 | 0.86 | MAPKAPK5 (0.41) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22123692 | 0.83 | MAPKAPK5 (0.43) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL24112349 | 0.83 | MAPKAPK5 (0.41) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22154245 | 0.83 | MAPKAPK5 (0.42) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22124330 | 0.82 | MAPKAPK5 (0.42) | TTKMAPKAPK5PTK6SYKAURKB | |
| SCHEMBL22139063 | 0.82 | PTK6 (0.49) | TTKMAPKAPK5PTK6AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |