Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 5/20 | 0.47 |
| ▸ | TTK | P33981 | 12/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123409 | 0.90 | PTK6 (0.44) | PTK6TTKAURKAMAPKAPK5 | |
| SCHEMBL25014255 | 0.88 | TTK (0.48) | PTK6TTKMAPKAPK5 | |
| SCHEMBL25013246 | 0.86 | TTK (0.48) | PTK6TTKAURKAMAPKAPK5 | |
| SCHEMBL22123030 | 0.80 | PTK6 (0.47) | PTK6TTK | |
| Hydrochloric Acid SCHEMBL30171859 | 0.80 | PTK6 (0.47) | PTK6TTK | |
| SCHEMBL25013054 | 0.79 | PTK6 (0.57) | PTK6 | |
| SCHEMBL22122995 | 0.79 | TTK (0.46) | PTK6TTKAURKA | |
| SCHEMBL25013086 | 0.79 | PTK6 (0.54) | PTK6TTK | |
| SCHEMBL22122897 | 0.78 | TTK (0.46) | PTK6TTKMAPKAPK5 | |
| SCHEMBL25013102 | 0.78 | TTK (0.53) | PTK6TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |