Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.54 |
| ▸ | TTK | P33981 | 6/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.43 |
| ▸ | LCK | P06239 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123139 | 0.90 | PTK6 (0.51) | PTK6TTKAURKBLCK | |
| SCHEMBL25013102 | 0.89 | TTK (0.53) | PTK6TTK | |
| SCHEMBL25013672 | 0.87 | TTK (0.55) | PTK6TTK | |
| SCHEMBL25013088 | 0.85 | TTK (0.51) | PTK6TTK | |
| SCHEMBL25014250 | 0.85 | TTK (0.48) | PTK6TTK | |
| SCHEMBL25014255 | 0.85 | TTK (0.48) | PTK6TTK | |
| SCHEMBL30183403 | 0.84 | PTK6 (0.47) | PTK6TTKAURKBLCK | |
| SCHEMBL22124725 | 0.83 | PTK6 (0.49) | PTK6TTKAURKBLCK | |
| SCHEMBL25013288 | 0.82 | TTK (0.47) | PTK6TTK | |
| SCHEMBL25013812 | 0.81 | MAPKAPK5 (0.49) | PTK6TTKAURKBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |