Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.55 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24870734 | 0.94 | TTK (0.54) | TTKPTK6 | |
| SCHEMBL30171787 | 0.94 | TTK (0.54) | TTKPTK6 | |
| SCHEMBL22123056 | 0.93 | TTK (0.52) | TTKPTK6 | |
| SCHEMBL25013102 | 0.91 | TTK (0.53) | TTKPTK6 | |
| SCHEMBL22123473 | 0.90 | TTK (0.52) | TTKPTK6 | |
| SCHEMBL25013086 | 0.87 | PTK6 (0.54) | TTKPTK6 | |
| SCHEMBL25013246 | 0.87 | TTK (0.48) | TTKPTK6 | |
| SCHEMBL22122852 | 0.85 | TTK (0.50) | TTKPTK6 | |
| SCHEMBL22123168 | 0.85 | TTK (0.50) | TTKPTK6 | |
| SCHEMBL22123076 | 0.85 | TTK (0.47) | TTKPTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |