Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.57 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25013088 | 0.83 | TTK (0.51) | TTKMAPKAPK5 | |
| SCHEMBL22123685 | 0.83 | TTK (0.47) | TTKMAPKAPK5 | |
| SCHEMBL22122864 | 0.82 | TTK (0.46) | TTKMAPKAPK5 | |
| SCHEMBL22123471 | 0.81 | TTK (0.46) | TTKMAPKAPK5 | |
| SCHEMBL22123006 | 0.81 | TTK (0.46) | TTKMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL30171868 | 0.81 | TTK (0.45) | TTKMAPKAPK5 | |
| SCHEMBL22122920 | 0.80 | TTK (0.48) | TTKMAPKAPK5 | |
| SCHEMBL22124774 | 0.80 | TTK (0.53) | TTKMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL30171549 | 0.80 | TTK (0.52) | TTKMAPKAPK5 | |
| SCHEMBL3467955 | 0.80 | TTK (0.50) | TTKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |