Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948163 | 1.00 | CCR5 (0.36) | CCR5FUCA1ALDH1A1HTR2CCHRNB2 | |
| SCHEMBL17121782 | 0.95 | CCR5 (0.36) | CCR5FUCA1HTR2CCHRNB2CHRNB4 | |
| SCHEMBL26880045 | 0.82 | FUCA1 (0.32) | FUCA1 | |
| SCHEMBL27388495 | 0.80 | HTR2C (0.36) | HTR2C | |
| SCHEMBL19963422 | 0.80 | HTR2C (0.33) | HTR2C | |
| SCHEMBL24773886 | 0.79 | CCR5 (0.35) | CCR5ALDH1A1 | |
| SCHEMBL24588800 | 0.76 | CCR5 (0.36) | CCR5FUCA1HTR2CCHRNB2CHRNB4 | |
| SCHEMBL18781491 | 0.76 | CCR5 (0.36) | CCR5FUCA1HTR2CCHRNB2CHRNB4 | |
| SCHEMBL8259176 | 0.74 | CCR5 (0.44) | CCR5ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24365327 | 0.73 | HTR2C (0.37) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002409-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |