SCHEMBL25015136

SCHEMBL25015136

CC(=O)OCCSc1ccc(C#Cc2ccc(COc3ccc(C#Cc4ccc(CCOC(C)=O)cc4)cc3)cc2C)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACACB O00763 7/20 0.43
FFAR1 O14842 10/20 0.41
MRGPRX4 Q96LA9 1/20 0.37
CHRM2 P08172 1/20 0.37
S1PR1 P21453 1/20 0.37
FPR1 P21462 1/20 0.37
FPR3 P25089 1/20 0.37
GPR183 P32249 1/20 0.37
APLNR P35414 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
GPR65 Q8IYL9 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25015298 0.89 FFAR1 (0.43) ACACBFFAR1CHRM2S1PR1FPR1
SCHEMBL24802692 0.79 ACACB (0.51) ACACBFFAR1FFAR4
SCHEMBL24802691 0.79 ACACB (0.51) ACACBFFAR1FFAR4
SCHEMBL25015185 0.77 FFAR1 (0.40) ACACBFFAR1CHRM2S1PR1FPR1
SCHEMBL25015146 0.74 PPARD (0.40) ACACBFFAR1MRGPRX4FFAR4MEN1
SCHEMBL25015299 0.73 MAOB (0.43) ACACBMEN1KMT2APPARA
SCHEMBL25015143 0.73 PPARA (0.41) ACACBFFAR1MRGPRX4FFAR4PPARD
SCHEMBL24802693 0.72 FFAR4 (0.46) ACACBFFAR1MRGPRX4FFAR4
SCHEMBL25015144 0.72 FFAR1 (0.35) ACACBFFAR1MEN1KMT2APPARD
SCHEMBL24487378 0.69 ACACB (0.50) ACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT SP1, C5, ZYX ACACB 3334/4885FFAR1 2652/4885MRGPRX4 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.