SCHEMBL25015144

SCHEMBL25015144

CC(=O)OCCSc1ccc(C#Cc2ccc(O)c(C)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.35
HNF4A P41235 1/20 0.35
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
ACACB O00763 2/20 0.33
PTPN11 Q06124 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
ALDH1A1 P00352 4/20 0.32
MAPT P10636 3/20 0.32
RECQL P46063 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25015299 0.79 MAOB (0.43) PPARAACACBMEN1KMT2AMTNR1A
SCHEMBL25015146 0.78 PPARD (0.40) FFAR1PPARDPPARAACACBMEN1
SCHEMBL25015143 0.77 PPARA (0.41) FFAR1PPARDPPARAACACB
SCHEMBL25015312 0.76 MTNR1A (0.35) PPARDPPARAACACBMEN1KMT2A
SCHEMBL25015308 0.76 GABRA1 (0.35) ACACBMEN1KMT2AMTNR1AMTNR1B
SCHEMBL25015145 0.76 PPARD (0.38) FFAR1PPARDPPARAACACB
SCHEMBL25015310 0.75 MTNR1A (0.38) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL24806608 0.74 THRB (0.37) FFAR1PPARDPPARAACACBMEN1
SCHEMBL25015298 0.74 FFAR1 (0.43) FFAR1ACACBALDH1A1RECQLCYP1A2
SCHEMBL1710082 0.74 ALDH1A1 (0.49) ALDH1A1MAPTSMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT SP1, C5, ZYX FFAR1 2652/4885HNF4A 3230/4885PPARD 4531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.