Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641883 | 0.78 | CYP2C9 (0.45) | CYP2C9ALDH1A1TSHRFFAR3LCK | |
| SCHEMBL11162924 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11162927 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1783630 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL1783632 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL52160 | 0.69 | — | — | |
| SCHEMBL11571116 | 0.69 | CYP2C9 (0.39) | CYP2C9ALDH1A1TSHR | |
| SCHEMBL11571120 | 0.69 | CYP2C9 (0.39) | CYP2C9ALDH1A1TSHR | |
| SCHEMBL3632057 | 0.67 | — | — | |
| SCHEMBL11572530 | 0.67 | TSHR (0.47) | CYP2C9ALDH1A1TSHRFFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350190-A1 | BRØNSTED-ACID FLUOROALKYL PHOSPHONATES | Merck Patent GmbH (DE) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017045745-A1 | BRØNSTED-ACID FLUOROALKYL PHOSPHONATES | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| WO-2015000543-A1 | RARE EARTH METAL-BIS(PERFLUOROALKYL)PHOSPHINATES AS LEWIS ACID CATALYSTS | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | WO | disclosed |
| US-8551984-B2 | Aminopyrimidines as SYK inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20110245205-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME LLC | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245205-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | SYK, BTK, LCK | CYP2C9 1267/4885ALDH1A1 1614/4885TSHR 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.