SCHEMBL2501577

SCHEMBL2501577

Cc1n[nH]c(-c2ccc(Cl)cc2)c1C(C)C(=O)O.Cc1nn(-c2cncs2)c(-c2ccc(Cl)cc2)c1C(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.33
CNR2 P34972 4/20 0.31
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1360293 0.91 CNR2 (0.36) CNR2CNR1
SCHEMBL1361986 0.79 TYMP (0.44) TYMP
SCHEMBL1431030 0.73 CYP1A2 (0.37) CNR2CNR1
SCHEMBL1359451 0.73 CNR2 (0.38) CNR2CNR1
SCHEMBL2035679 0.72 BRD4 (0.42) TYMPCNR2CNR1
SCHEMBL1359508 0.72 PTGDR2 (0.39) CNR2CNR1
SCHEMBL1430934 0.71 CYP1A2 (0.37) CNR2CNR1
SCHEMBL2534665 0.70 TP53 (0.36) TYMPCNR2CNR1
SCHEMBL2505082 0.67 CNR1 (0.33) CNR2CNR1
SCHEMBL2010705 0.63 CNR2 (0.35) TYMPCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373648-A1 SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOLE-4-YL-ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Bayer CropScience AG (DE) 2011-10-12 EP disclosed