Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359508 | 0.74 | PTGDR2 (0.39) | CNR1CNR2 | |
| SCHEMBL2501577 | 0.67 | TYMP (0.33) | CNR1CNR2 | |
| SCHEMBL15653888 | 0.63 | MEN1 (0.44) | SLC22A12 | |
| SCHEMBL7550366 | 0.63 | MEN1 (0.44) | SLC22A12 | |
| SCHEMBL3554824 | 0.58 | CHRM3 (0.44) | — | |
| SCHEMBL12859317 | 0.56 | PDE2A (0.42) | CNR1CNR2 | |
| SCHEMBL15143119 | 0.56 | NAPRT (0.41) | — | |
| SCHEMBL1431030 | 0.55 | CYP1A2 (0.37) | CNR1CNR2 | |
| SCHEMBL4512658 | 0.55 | AVPR2 (0.38) | CNR1CNR2 | |
| SCHEMBL22758103 | 0.54 | KMT2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373648-B1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YL ACETIC ACIDS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-2373648-A1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOLE-4-YL-ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010063422-A1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOLE-4-YL-ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | WO | disclosed |
| EP-2194052-A1 | Substituted 1.(1-thiazolyl)- and 1-(isothiazolyl)pyrazol-4-yl acetic acids, method for their production and their use as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2010-06-09 | — | — | EP | disclosed |