Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.49 |
| ▸ | F2 | P00734 | 10/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25017370 | 0.92 | F10 (0.51) | F10F2PRSS1SMN1; SMN2POLB | |
| SCHEMBL25016191 | 0.89 | F10 (0.49) | F10F2PRSS1SMN1; SMN2POLB | |
| SCHEMBL25016230 | 0.87 | F10 (0.47) | F10F2PRSS1SMN1; SMN2PTGS2 | |
| SCHEMBL25016257 | 0.87 | F10 (0.45) | F10F2PRSS1PTGS2 | |
| SCHEMBL25016241 | 0.85 | F10 (0.50) | F10F2PRSS1SMN1; SMN2TSHR | |
| SCHEMBL25016256 | 0.83 | F10 (0.44) | F10F2PRSS1PTGS2 | |
| SCHEMBL25015748 | 0.83 | F10 (0.44) | F10F2PRSS1 | |
| SCHEMBL25015740 | 0.82 | F10 (0.50) | F10F2PRSS1SMN1; SMN2MAPT | |
| SCHEMBL25017882 | 0.80 | F10 (0.44) | F10F2PRSS1PTGS2 | |
| SCHEMBL25016232 | 0.79 | F10 (0.52) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | F10 1548/4885F2 408/4885PRSS1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.