MMP7 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL328472	0.54	17/20
SCHEMBL328486	0.53	17/20
SCHEMBL328559	0.50	15/20
SCHEMBL255167	0.54	10/20
SCHEMBL328467	0.50	10/20
SCHEMBL255126	0.67	9/20
SCHEMBL254532	0.56	9/20
Prinomastat (SCHEMBL115696)	1.00	8/20
SCHEMBL254535	0.65	8/20
SCHEMBL159724	0.48	8/20
SCHEMBL314001	0.82	7/20
SCHEMBL405125	0.66	7/20
SCHEMBL174865	0.59	7/20
SCHEMBL667611	0.47	6/20
SCHEMBL32038	0.45	6/20
Hydrochloric Acid (SCHEMBL59932)	0.39	6/20
Hydrochloric Acid (SCHEMBL60916)	0.39	6/20
Hydrochloric Acid (SCHEMBL82688)	0.39	6/20
Bromide (SCHEMBL351568)	0.39	6/20
Bromide (SCHEMBL414762)	0.39	6/20

Clinical trials — most relevant to MMP7 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer	PHASE2	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Peri-implantitis and MMP-8	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries	nan	RECRUITING
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia	nan	UNKNOWN
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Value of Cortactin Expression in Invasive and Non-invasive Urinary Bladder Urothelial Carcinoma in Egyptian Population	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Salivary Markers in Periodontal Disorders	nan	COMPLETED
To Study the Effects of Host Genetic Factors on Liver Cirrhosis and Hepatocellular Carcinoma (HCC)	nan	UNKNOWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP7 binder may also engage these)

Protein	Name	Similarity
Q10738	—	1.000	Q10738 →
P50280	—	1.000	P50280 →
P57748	—	0.996	P57748 →
P55032	—	0.996	P55032 →
MMP1	Interstitial collagenase	0.994	landscape →
O18767	—	0.994	O18767 →
MMP20	Matrix metalloproteinase-20	0.994	landscape →
Q10835	—	0.993	Q10835 →
O55123	—	0.993	O55123 →
O70138	—	0.992	O70138 →
P07152	—	0.992	P07152 →
Q6Y4Q5	—	0.992	Q6Y4Q5 →
P53690	—	0.992	P53690 →
Q95220	—	0.991	Q95220 →
MMP8	Neutrophil collagenase	0.991	landscape →
MMP12	Macrophage metalloelastase	0.991	landscape →
Q63341	—	0.991	Q63341 →
O13065	—	0.991	O13065 →
Q10739	—	0.991	Q10739 →
MMP3	Stromelysin-1	0.991	landscape →
Q9EPL5	—	0.991	Q9EPL5 →
MMP14	Matrix metalloproteinase-14	0.990	landscape →
P79287	—	0.990	P79287 →
MMP10	Stromelysin-2	0.990	landscape →
O62806	—	0.990	O62806 →
O88766	—	0.990	O88766 →
Q9GLE4	—	0.989	Q9GLE4 →
P34960	—	0.989	P34960 →
P28863	—	0.989	P28863 →
P28053	—	0.989	P28053 →