⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25018158 | 0.94 | LMNA (0.32) | — | |
| SCHEMBL25017626 | 0.90 | HDAC6 (0.30) | — | |
| SCHEMBL25018018 | 0.82 | — | — | |
| SCHEMBL25017794 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL25017522 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL25017628 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL25515667 | 0.78 | NR1I2 (0.31) | — | |
| SCHEMBL25017713 | 0.77 | HDAC6 (0.33) | — | |
| SCHEMBL25017335 | 0.76 | NR1I2 (0.33) | — | |
| SCHEMBL26778526 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143804-A1 | FLUOROALKYL-OXADIAZOLES AND USES THEREOF | TENAYA THERAPEUTICS, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11578066-B1 | Fluoroalkyl-oxadiazoles and uses thereof | TENAYA THERAPEUTICS, INC. (US) | 2023-02-14 | — | — | US | disclosed |